Checked with both my wife and brother-in-law, who grew up in Louisville. She didn't recognize the building, but my bro-in-law used to work at the Ford plant until he changed careers about seven years ago. This was what he emailed back to me. (I don't know his reference source.)
"This photo may have been taken at the old ford model t assembly plant in Louisville - it was located next door to the University of Louisville:
Ford Motor Company began manufacturing Model T cars in Louisville in 1913, at 931 South Third Street. A new four story assembly plant at Third & Eastern Parkway opened in 1916. In 1925 Ford moved production to a new, one level assembly plant on Southwestern Parkway, on the Ohio River.. The current plant on Fern Valley Road opened in 1955. Most Edsel automobiles (around 67%) were produced here in 1957-1959. Other models produced included Sunliners, Fairlanes & Galaxies . Louisville Assembly also produced heavy trucks as well as full-size cars on a separate assembly line. Heavy truck production ceased when the Kentucky Truck Plant opened on Chamberlain Lane in 1969. The factory continued with passenger car production that was augmented in 1973 with the addition of F-Series light trucks. F-Series/LTD passenger car production continued until 1981 when the plant was shut down for retooling for the new compact pickup, the Ranger, and its SUV cousin, the Bronco II. Production began in January 1982. Ford produced its two millionth Ranger/Bronco II at the plant on April 26, 1988. On February 14, 1990, Ford began producing the Explorer SUV in Louisville after investing $563 million at the plant. It produced one million Explorers as of August 27, 1993. Production of the similar Mercury Mountaineer began in April 1996, and Ranger production gave way in April 1999 to the Explorer Sport Trac."
Here's a photo of my Explorer Sport Trac: