It's straight and the threads are excellent. The depression in the center is ¼" deep. My guess is that it won't be a problem. Agree?
I don't think it should present any real problems, but I'm curious........an original Ford part or something from a vendor?
I should have added, is the metal uniform thickness throughout? If that depression is thin, well yeah, that might be an issue.
Is it actually straight? Many manifolds that are "straightened" by the popular methods, as this manifold appears to have been, are not actually straight. They are OK up and down, but not front to back, which is just as important if you expect the rings to fit correctly.
You can easily check the hole spacing with a set of calipers. The narrow holes are 2.062", inside edge to inside edge. The two sets of wide holes are 4.875" inside edge to inside edge.
If it is actually straight, it should work fine, IMHO.
This one he been “straightened”. I made a jig to do that job and ended up ruining a manifold very much like this. They slump and burn through, even if you are careful.
This one looks useable, but cylinder #1  won’t breathe as well as #3 & #4!
It has been straightened by breaking it and welding back together. Should work fine as long as the weld is good.
I agree. See this video on "Engine Masters" where they show that extreme bashing of header tubes for clearance resulted in NO horsepower loss.